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CDC under investigation over Katrina cancer risk

Congressional committee also looks into whether agency retaliated against scientist
ALISON YOUNG
Atlanta Journal-Constitution
February 9, 2008

A congressional committee is investigating "disturbing allegations" that officials at the Centers for Disease Control and Prevention suppressed critical information about cancer dangers posed by trailers housing Hurricane Katrina victims.

The committee also is looking into whether the Atlanta scientist who sought to make the risks public has been the subject of retaliation by the agency.

In a letter this week to CDC Director Julie Gerberding, committee members warned that they expect her to protect the scientist, Christopher De Rosa.

"The agency's conduct has called into question its ability to investigate public health hazards accurately and appropriately in the future," wrote the chairman and two subcommittee chairmen from the House Committee on Science and Technology in a letter Wednesday to Gerberding.

"Apparently in retaliation, Dr. De Rosa was removed from his post and given a job ... that appears to include no real responsibilities," the letter said.

CDC spokesman Glen Nowak said Friday the agency has not suppressed any science, nor has it retaliated against De Rosa. "The integrity of CDC's science is paramount to everything we do," Nowak said.

De Rosa had been head of the division of toxicology and environmental medicine in CDC's Agency for Toxic Substances and Disease Registry since 1992. He was removed from that job last fall and assigned the title of "special assistant."

Though CDC said De Rosa was simply reassigned, he said in an interview that he's been demoted. De Rosa said the public should be concerned about what's transpired.

"The very people they're looking to for answers have been censored," he said.

At issue is whether the agency intentionally delayed or avoided examining the long-term cancer threat posed by formaldehyde fumes in trailers purchased by the Federal Emergency Management Agency to house victims of the August 2005 hurricane. FEMA initially said air quality in the trailers was safe if they were properly ventilated.

Formaldehyde is a colorless gas with a pungent smell. It is used in the production of plywood and resins. Some studies have linked exposure to formaldehyde with nose and throat cancer.

The committee also is investigating whether CDC abruptly stopped publication of another report involving De Rosa, detailing "disturbing potential health issues" in the Great Lakes region of the U.S., the letter said. The report examined areas with environmental pollution and found elevated levels of certain cancers and other health problems but did not make any cause-and-effect link.

"I want to find out what really happened," said Rep. Brad Miller (D-N.C.), chairman of the Subcommittee on Investigations and Oversight, Friday evening.

It's the latest incident involving allegations that CDC's scientific findings on environmental issues are being watered down.

In October, another committee investigated the White House's involvement in the cutting of nearly seven pages of information about the health consequences of climate change. The deletions were from written testimony Gerberding had planned to give to Congress. Gerberding, however, was adamant she had not been censored.

Nowak said CDC's actions were focused on maintaining high standards of science. He said the Great Lakes report was pulled from publication because parts of it were misleading and didn't meet standards of scientific rigor. The committee is investigating whether agency managers "intentionally circumvented" De Rosa in an initial review of potential dangers associated with the trailers.

FEMA wanted ATSDR to look only at the health effects of short-term formaldehyde exposure -- defined as less than two weeks. Yet many Katrina residents have lived in the trailers for months and years, the committee said in its letter.

De Rosa, the committee's letter said, already had raised questions about the long-term health effects and agency managers knew he would insist the report not be confined to short-term effects. Formaldehyde is a suspected carcinogen that has no safe level set for long-term exposure, the letter said.

"De Rosa was then specifically and consciously excluded in the health assessment," said Miller, referring to information provided to the committee.

Miller said information reviewed by the committee indicates FEMA's requests of CDC were driven by concerns about legal liability, not public health.

FEMA officials declined to be interviewed Friday. But in written statements, they have said the agency didn't ignore, hide or manipulate research. They said the health and safety of hurricane victims was their top priority at all times.

Nowak, the CDC spokesman, said the agency initially focused solely on short-term effects because that's what FEMA asked CDC to look at. But he said the agency later issued a supplemental report with information about long-term health effects.

"Nobody was ignoring the fact that formaldehyde had longer-term health consequences," Nowak said. The agency has been sampling the air quality in more than 500 trailers in Louisiana and Mississippi and is now in the process of analyzing the data.

Congressional investigators, however, said CDC only amended the report to include long-term exposure warnings eight months later -- after De Rosa "persistently demanding" they be included.

De Rosa said Friday that he raised his concerns about formaldehyde, the Great Lakes report and other issues through proper channels within the CDC.

"It's sort of like speaking truth to authority. I knew I was doing it at my peril," he said.

Then, in what investigators said was apparently retaliation, De Rosa was removed from his managerial job and in October given an "unsatisfactory" job performance assessment. Before, De Rosa said, he had received good to excellent ratings.

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 FAQ

Symptoms of Formaldehyde Exposure:

Asthma Attacks
Blurred Vision
Eye irritiation
Shortness of Breath
Sinus Infections
Skin rashes
Coughing
Dizziness
Headaches
Nausea
Nosebleeds
Wheezing
Formaldehyde has been classified as a human carcinogen (cancer-causing substance) by the International Agency for Research on Cancer and as a probable human carcinogen by the U.S. Environmental Protection Agency

What is Formaldehyde?

Formaldehyde is an important industrial chemical used to make other chemicals, building materials, and household products. It is one of the large family of chemical compounds called volatile organic compounds or 'VOCs'. The term volatile means that the compounds vaporize, that is, become a gas, at normal room temperatures.

What are the short-term health effects of formaldehyde exposure?

When formaldehyde is present in the air at levels exceeding 0.1 ppm, some individuals may experience health effects such as watery eyes; burning sensations of the eyes, nose, and throat; coughing; wheezing; nausea; and skin irritation. Some people are very sensitive to formaldehyde, while others have no reaction to the same level of exposure.

Can formaldehyde cause cancer?


Although the short-term health effects of formaldehyde exposure are well known, less is known about its potential long-term health effects. In 1980, laboratory studies showed that exposure to formaldehyde could cause nasal cancer in rats. This finding raised the question of whether formaldehyde exposure could also cause cancer in humans. In 1987, the U.S. Environmental Protection Agency (EPA) classified formaldehyde as a probable human carcinogen under conditions of unusually high or prolonged exposure (1). Since that time, some studies of industrial workers have suggested that formaldehyde exposure is associated with nasal cancer and nasopharyngeal cancer, and possibly with leukemia. In 1995, the International Agency for Research on Cancer (IARC) concluded that formaldehyde is a probable human carcinogen. However, in a reevaluation of existing data in June 2004, the IARC reclassified formaldehyde as a known human carcinogen (2).
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